Edit: Nvm I fixed it by typing “tcai” in the console followed by “enableplayercontrols”, then cast a “calm” spell on Harkon
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You probably joined the dawnguard or attacked one of the vampire clan at some point. Sheathe your weapon/magic before entering and they might chill out. This only works once, so if that fails you might need console commands to fix it.
https://en.m.uesp.net/wiki/Skyrim:Console
I’m not sure which command to use but I recommend creating a separate save file before messing with this. Sometimes flipping these settings will mess with certain quests and create glitches.