I hear ashwaganda actually helps? Anyone tried it?

Please do not recommend weed

And if you say alcohol you’re a very fine comedian

  • ReadFanon [any, any]@hexbear.netEnglish
    9·
    2 months ago

    Some psychiatrists are prescribing buproprion and DXM under separate scripts but in the same dosages as Auvelity to achieve the exact same outcome.

    DXM will still work on its own, without bupropion, but it won’t be nearly as effective as an antidepressant.

    • cosecantphi [he/him]@hexbear.netEnglish
      5·
      2 months ago

      Yeah it’s hard to say how effective DXM is on its own, I’m not sure whether there’s much research on it if any. But it’s worth noting because it’s definitely an SNRI. I know some people who don’t tolerate Bupropion very well, in those cases it might be worth trying.

      • rayne [she/her]@hexbear.netEnglish
        1·
        2 months ago

        It’s only an SNRI in its pro drug form, which is DXM. The reason it is prescribed with Wellbutrin is because it prevents your body from turning DXM into DXO, which is a powerful disassociative.

        Additionally the half-life of DXM doesn’t make it a very effective SNRI without changing the body’s metabolism. The Wellbutrin is the component that changes metabolism.

        I’ve done a lot of personal research with both DXM and it’s active metabolite. And have some undergraduate education in pharmacology. I really don’t recommend it.