I know you can get estrogen from horse urine as a feedstock, but there are other methods used today, right? Do they use other animal products? Petroleum? I’m just looking for a basic overview and don’t know where else to look.

  • Sam [none/use name]@hexbear.net
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    6 months ago

    For the purposes of HRT, regardless of application, there are two main estrogens to consider; Estrone (E1) and Estradiol (E2).

    Estrone is a weak estrogen in the body it is derived from cholesterol. However, in its most common form of medication, Premarin, it is derived from the urine of pregnant mares. As a weak estrogen that is also not bioidentical (Premarin’s chemical structure differs from organic estrone) , it is not as effective as Estradiol in the role of HRT.

    Estradiol is the major female sex hormone and as such in it’s synthesised ester forms such as Estradiol Valerate it is often considered the most effective form of HRT. It can be derived from diosgenin found in yams, or stigmaserol usually from soybean oil and probably some other plant precursors Im not aware of. It should be noted that most sex hormones can be derived from these methods, stigmaserol for example converts to estrone before it is chemically altered to estradiol.

    • EstraDoll [she/her]@hexbear.net
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      6 months ago

      Estradiol Valerate it is often considered the most effective form of HRT. It can be derived from diosgenin found in yams,

      injecting my legs full of that tuber juice