I have small hands and still fingertip basically all the time, and I have all my life. I don’t use a small mouse either (G502)
I hate how smudgy and uncomfortable it feels to have reduced fine control when my palm comes into contact with the mouse. It feels icky and frustrating. I know plenty of people palm grip with low DPI and big mousepads to achieve fine control, but that seems far more exhausting than just developing stamina in the forearm.
Yeah it’s a “read the room” kind of thing.
There’s a group that would be annoyed by immersion-breaking 4th wall jokes, and there’s another group that would be relieved by the tension and pressure to perform being broken. Everyone’s going to have slightly different comfort levels so there’s always some compromise on the tone of a campaign.