Should be “trivial”, yes. The central OS components (e.g. systemd or whatever) shouldn’t care about anything in your home directories. Only apps that store your user preferences, user DBs, etc. there should. So you might have some old hidden directories that won’t be used anymore, some that hopefully different versions of the same apps if applicable can migrate the data from, etc. But it shouldn’t affect the general functioning of your OS.
It wouldn’t be a bad idea to first 1. backup the home directory, in case any app data migrations mess things up somehow, and 2. create a user with a home directory path that didn’t exist in the old dir structure, in case you need to login as that user to fix things (e.g. let’s say your profile or shell resource script has something that a new shell version in the new distro doesn’t understand and that keeps you from logging in).
Should be “trivial”, yes. The central OS components (e.g. systemd or whatever) shouldn’t care about anything in your home directories. Only apps that store your user preferences, user DBs, etc. there should. So you might have some old hidden directories that won’t be used anymore, some that hopefully different versions of the same apps if applicable can migrate the data from, etc. But it shouldn’t affect the general functioning of your OS.
It wouldn’t be a bad idea to first 1. backup the home directory, in case any app data migrations mess things up somehow, and 2. create a user with a home directory path that didn’t exist in the old dir structure, in case you need to login as that user to fix things (e.g. let’s say your profile or shell resource script has something that a new shell version in the new distro doesn’t understand and that keeps you from logging in).