It entirely depends on the cat, and generally speaking, the earlier you teach a kitten that human contact is a good thing the more likely they will be receptive of it. Cats are most impressionable the first 10-12 weeks of their life, after that its really hard to convince them to change. We have two cats that were raised in a great foster home that we adopted at around 12 weeks and they will literally let you do anything; I think its like 50% genes and 50% how they were raised