Preclinical studies suggest a drug-free nasal spray could ward off respiratory infections
www.eurekalert.org
A new study details how a nasal spray formulated by investigators from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, may work to protect against viral and bacterial respiratory infections

The spray is called “Pathogen Capture and Neutralizing Spray” (PCANS) for now

This data suggest PCANS as a promising daily-use prophylactic against respiratory infections.

The study is paywalled, and the abstract doesn’t list its ingredients beyond

The formulation consists of excipients identified from the FDA’s Inactive Ingredient Database and Generally Recognized as Safe list to maximize efficacy for each step in the multi-modal approach.

Based on that description, its ingredients might not be very different from Covixyl, though it claims to be much more effective.

Edit: Apparently its already for sale, I included some details in a comment

  • TheModerateTankie [any]@hexbear.netEnglish
    5·
    2 days ago

    Iota-carageenan based sprays operate on the same principle. Basically coats your nasal passage with a gel that traps virus, bacteria, and allergens.

    The one I use helps with allergies so it’s doing something, and I convinced someone I know who works in small office and got pressured out of masking at work (plus they couldn’t find a mask that works with their glasses), and they run an air filter + nasal sprays like covixyl and betadine, along with yearly vaccines, and they haven’t gotten sick in over a year.

    But I’ve also read enough anecdotal reports from people who use them and still got sick with covid. Who knows if they were properly applied, but I doubt these sprays alone will do much if your exposure levels are high.

    Still iI think t’s probably worth trying to protect your olfactory bulb with these sprays, since that’s at least one of the ways they think covid can enter the brain.

    • sovietknuckles [they/them]@hexbear.netOPEnglish
      3·
      1 day ago

      plus they couldn’t find a mask that works with their glasses

      Most KN95s and all N95s I have tried fog my glasses. But ProGear N95s don’t, that’s the kind that I prefer. Once you put it on, you can press the metal nose band to fit it to your exact nose shape

      But I’ve also read enough anecdotal reports from people who use them and still got sick with covid. Who knows if they were properly applied,

      Maybe it’s important to get one with a good spray. The Betadine iota carrageenan spray is very good, with respect to diffusion. It also doesn’t require shaking or spraying beforehand to get a full spray.

      Some Covixyl bottles don’t diffuse the spray well, and it’s very noticeable

      but I doubt these sprays alone will do much if your exposure levels are high.

      yea

      And if there’s enough COVID in the air, you can get COVID in your eyes, not just your nose. Wearing Stoggles helps if someone coughs in your direction, but not if there’s just lots of COVID in the air