I wrote the research team and have skimmed the article. Dose regimen was 0.05mg/kg every other day. This would be about 0.25mg in an adult female human. Or about 0.25g of moderate potency cubensis. Half that or less of strong cubensis (PE/APE/etc).

  • antlion@lemmy.dbzer0.com
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    1 year ago

    This seems kind of silly to me. This is a drug that affects the brain, and that is nearly harmless at the microdose level. Just test on human volunteers. That way your results have useful clinical meaning. You can’t really ask the rats how they felt after the regimen.

    • treefrog@lemm.eeOP
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      1 year ago

      They are, but placebo makes it difficult to measure.

      This study proves more is going on then placebo and will surely help more funding go into human studies.

      It’s certainly not silly. But I keep pet rats and I do find the methods used in animal studies often cruel. This one included.

      But it’s not silly.

    • HubertManne@kbin.social
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      1 year ago

      Yeah usually animal models are used because of danger to humans but we have plenty of evidence this substance is harmless.

    • rjs001
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      11 months ago

      deleted by creator